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Paracrine and Transpresentation Functions of IL-15 Are Mediated by Diverse Splice Versions of IL-15Rα in Human Monocytes and Dendritic Cells

Species-specific differences of post-translational modifications suggested the existence of human IL-15Rα isoforms. We identified eight new isoforms that are predicted to modify the intracellular C termini of IL-15Rα, and another N-terminal exon “Ex2A” that was consistently present in all but one of...

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Autors principals: Müller, Jürgen R., Waldmann, Thomas A., Kruhlak, Michael J., Dubois, Sigrid
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504748/
https://ncbi.nlm.nih.gov/pubmed/23074221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.378612
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