Long-term Transgene Expression in the Central Nervous System Using DNA Nanoparticles

This study demonstrates proof of concept for delivery and expression of compacted plasmid DNA in the central nervous system. Plasmid DNA was compacted with polyethylene glycol substituted lysine 30-mer peptides, forming rod-like nanoparticles with diameters between 8 and 11 nm. Here we show that an...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Yurek, David M, Fletcher, Anita M, Smith, George M, Seroogy, Kim B, Ziady, Assem G, Molter, Joseph, Kowalczyk, Tomasz H, Padegimas, Linas, Cooper, Mark J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835115/
https://ncbi.nlm.nih.gov/pubmed/19223866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.2
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados