DNA Nanoparticles: Detection of Long-Term Transgene Activity in Brain Using Bioluminescence Imaging

In this study, we used bioluminescence imaging (BLI) to track long-term transgene activity following the transfection of brain cells using a nonviral gene therapy technique. Formulations of deoxyribonucleic acid (DNA) combined with 30-mer lysine polymers (substituted with 10 kDa polyethylene glycol)...

Full description

Saved in:
Bibliographic Details
Main Authors: Yurek, David M., Fletcher, Anita M., McShane, Matthew, Kowalczyk, Tomasz H., Padegimas, Linas, Weatherspoon, Marcy R., Kaytor, Michael D., Cooper, Mark J., Ziady, Assem G.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173525/
https://ncbi.nlm.nih.gov/pubmed/21521549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2310/7290.2010.00053
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items