Age and lesioned-induced increases of GDNF transgene expression in brain following intracerebral injections of DNA nanoparticles

In previous studies that used compacted DNA nanoparticles (DNP) to transfect cells in the brain, we observed higher transgene expression in the denervated striatum when compared to transgene expression in the intact striatum. We also observed that long term transgene expression occurred in astrocyte...

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Publicado en:Neuroscience
Main Authors: Yurek, DM, Hasselrot, U, Cass, WA, Sesenoglu-Laird, O, Padegimas, L, Cooper, MJ
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268246/
https://ncbi.nlm.nih.gov/pubmed/25453772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2014.10.026
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