DNA Nanoparticles: Detection of Long-Term Transgene Activity in Brain Using Bioluminescence Imaging

In this study, we used bioluminescence imaging (BLI) to track long-term transgene activity following the transfection of brain cells using a nonviral gene therapy technique. Formulations of deoxyribonucleic acid (DNA) combined with 30-mer lysine polymers (substituted with 10 kDa polyethylene glycol)...

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Autors principals: Yurek, David M., Fletcher, Anita M., McShane, Matthew, Kowalczyk, Tomasz H., Padegimas, Linas, Weatherspoon, Marcy R., Kaytor, Michael D., Cooper, Mark J., Ziady, Assem G.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173525/
https://ncbi.nlm.nih.gov/pubmed/21521549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2310/7290.2010.00053
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