Treatment of Pancreatic Cancer With an Oncolytic Adenovirus Expressing Interleukin-12 in Syrian Hamsters

Pancreatic cancer is an aggressive malignancy resistant to most conventional and experimental therapies, including conditionally replicative adenoviruses (CRAds). The incorporation of immunostimulatory genes such as interleukin-12 (IL-12) in these viruses may overcome some of their limitations, but...

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Bibliographische Detailangaben
Hauptverfasser: Bortolanza, Sergia, Bunuales, Maria, Otano, Itziar, Gonzalez-Aseguinolaza, Gloria, Ortiz-de-Solorzano, Carlos, Perez, Daniel, Prieto, Jesus, Hernandez-Alcoceba, Ruben
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2009
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835109/
https://ncbi.nlm.nih.gov/pubmed/19223865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.9
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