Evaluation of Monocytes as Carriers for Armed Oncolytic Adenoviruses in Murine and Syrian Hamster Models of Cancer

Replication-competent (oncolytic) adenoviruses (OAV) can be adapted as vectors for the delivery of therapeutic genes, with the aim of extending the antitumor effect beyond direct cytolysis. Transgene expression using these vectors is usually intense but short-lived, and repeated administrations are...

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Detalhes bibliográficos
Main Authors: Bunuales, Maria, Garcia-Aragoncillo, Eva, Casado, Raquel, Quetglas, José Ignacio, Hervas-Stubbs, Sandra, Bortolanza, Sergia, Benavides-Vallve, Carolina, Ortiz-de-Solorzano, Carlos, Prieto, Jesus, Hernandez-Alcoceba, Ruben
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2012
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3523252/
https://ncbi.nlm.nih.gov/pubmed/22985305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2012.043
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