Evaluation of Monocytes as Carriers for Armed Oncolytic Adenoviruses in Murine and Syrian Hamster Models of Cancer

Replication-competent (oncolytic) adenoviruses (OAV) can be adapted as vectors for the delivery of therapeutic genes, with the aim of extending the antitumor effect beyond direct cytolysis. Transgene expression using these vectors is usually intense but short-lived, and repeated administrations are...

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Hlavní autoři: Bunuales, Maria, Garcia-Aragoncillo, Eva, Casado, Raquel, Quetglas, José Ignacio, Hervas-Stubbs, Sandra, Bortolanza, Sergia, Benavides-Vallve, Carolina, Ortiz-de-Solorzano, Carlos, Prieto, Jesus, Hernandez-Alcoceba, Ruben
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc. 2012
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3523252/
https://ncbi.nlm.nih.gov/pubmed/22985305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2012.043
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