Evaluation of Monocytes as Carriers for Armed Oncolytic Adenoviruses in Murine and Syrian Hamster Models of Cancer

Replication-competent (oncolytic) adenoviruses (OAV) can be adapted as vectors for the delivery of therapeutic genes, with the aim of extending the antitumor effect beyond direct cytolysis. Transgene expression using these vectors is usually intense but short-lived, and repeated administrations are...

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Autors principals: Bunuales, Maria, Garcia-Aragoncillo, Eva, Casado, Raquel, Quetglas, José Ignacio, Hervas-Stubbs, Sandra, Bortolanza, Sergia, Benavides-Vallve, Carolina, Ortiz-de-Solorzano, Carlos, Prieto, Jesus, Hernandez-Alcoceba, Ruben
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2012
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3523252/
https://ncbi.nlm.nih.gov/pubmed/22985305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2012.043
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