Tolerance Induction Using Lentiviral Gene Delivery Delays Onset and Severity of Collagen II Arthritis

The treatment of rheumatoid arthritis remains suboptimal; thus there is considerable interest in the development of strategies that mediate tolerance to autoantigens. Using lentiviral gene transfer in vivo, we expressed the immunodominant epitope of collagen type II (CII) on major histocompatibility...

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Bibliografiska uppgifter
Huvudupphovsmän: Gjertsson, Inger, Laurie, Karen L, Devitt, James, Howe, Steven J, Thrasher, Adrian J, Holmdahl, Rikard, Gustafsson, Kenth
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2009
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Original Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835107/
https://ncbi.nlm.nih.gov/pubmed/19174762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.299
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