Collagen epitope expression on B cells is sufficient to confer tolerance to collagen-induced arthritis

BACKGROUND: The mechanisms underlying tolerance induction and maintenance in autoimmune arthritis remain elusive. In a mouse model of rheumatoid arthritis, collagen type II (CII)-induced arthritis, we explore the contribution of B cells to antigen-specific tolerance. METHODS: To generate expression...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Andersson, Sofia E. M., Eneljung, Tove, Tengvall, Sara, Jirholt, Pernilla, Stern, Anna, Henningsson, Louise, Liang, Bibo, Thorarinsdottir, Katrin, Kihlberg, Jan, Holmdahl, Rikard, Mårtensson, Inga-Lill, Gustafsson, Kenth, Gjertsson, Inger
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4908726/
https://ncbi.nlm.nih.gov/pubmed/27301320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-016-1037-7
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