T cells that are naturally tolerant to cartilage-derived type II collagen are involved in the development of collagen-induced arthritis

INTRODUCTION: A discussion is ongoing regarding the possible role of cartilage-directed autoimmunity as a part of the pathogenesis of rheumatoid arthritis (RA). One possibility is that the association of RA with shared epitope-expressing DR molecules reflects a role for major histocompatibility comp...

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Hauptverfasser: Malmström, Vivianne, Bäcklund, Johan, Jansson, Liselotte, Kihlberg, Jan, Holmdahl, Rikard
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2000
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Primary Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC17814/
https://ncbi.nlm.nih.gov/pubmed/11056672
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