Mutational Derivatives of PhiC31 Integrase With Increased Efficiency and Specificity

ϕC31 integrase is a sequence-specific phage recombinase that can recombine two short DNA sequences called attB and attP. The enzyme can also promote genomic integration of plasmids carrying attB into native mammalian sequences having partial identity to attP. To increase the efficiency of integratio...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Keravala, Annahita, Lee, Solomon, Thyagarajan, Bhaskar, Olivares, Eric C, Gabrovsky, Vanessa E, Woodard, Lauren E, Calos, Michele P
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2008
Schlagworte:
Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834998/
https://ncbi.nlm.nih.gov/pubmed/19002165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2008.241
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge