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Long-Term Transgene Expression in Mouse Neural Progenitor Cells Modified with PhiC31 Integrase

Stem cells can potentially be utilized in combined gene/cell therapies for neural diseases. We examined the ability of the non-viral ϕC31 integrase system to promote stable transgene expression in mouse neural progenitor cells (mNPCs). ϕC31 integrase catalyzes the sequence-specific integration of at...

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Détails bibliographiques
Auteurs principaux: Keravala, Annahita, Ormerod, Brandi K., Palmer, Theo D., Calos, Michele P.
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2615000/
https://ncbi.nlm.nih.gov/pubmed/18606184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneumeth.2008.06.005
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