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Impact of Hydrodynamic Injection and phiC31 Integrase on Tumor Latency in a Mouse Model of MYC-Induced Hepatocellular Carcinoma

BACKGROUND: Hydrodynamic injection is an effective method for DNA delivery in mouse liver and is being translated to larger animals for possible clinical use. Similarly, ϕC31 integrase has proven effective in mediating long-term gene therapy in mice when delivered by hydrodynamic injection and is be...

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Detalhes bibliográficos
Main Authors: Woodard, Lauren E., Keravala, Annahita, Jung, W. Edward, Wapinski, Orly L., Yang, Qiwei, Felsher, Dean W., Calos, Michele P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2894073/
https://ncbi.nlm.nih.gov/pubmed/20614008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011367
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