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Efficient reversal of phiC31 integrase recombination in mammalian cells

Over the past decade, the integrase enzyme from phage phiC31 has proven to be a useful genome engineering tool in a wide variety of species, including mammalian cells. The enzyme efficiently mediates recombination between two distinct sequences, attP and attB, producing recombinant product sites, at...

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Detalhes bibliográficos
Main Authors: Farruggio, Alfonso P., Chavez, Christopher L., Mikell, Carlos L., Calos, Michele P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104159/
https://ncbi.nlm.nih.gov/pubmed/22933343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/biot.201200283
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