Enhanced Therapeutic Efficacy by Simultaneously Targeting Two Genetic Defects in Tumors

Targeting tumor-specific gene abnormalities has become an attractive approach in developing therapeutics to treat cancer. Overexpression of Bcl2 and mutations of p53 represent two of the most common molecular defects in tumors. In the nucleus, p53 induces cell cycle arrest, while it interacts with B...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Zhang, He, Wang, Haibo, Zhang, Jianjun, Qian, Guanxiang, Niu, Beibei, Fan, Xianqun, Lu, Jian, Hoffman, Andrew R., Hu, Ji-Fan, Ge, Shengfang
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2008
Gaiak:
Original Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834989/
https://ncbi.nlm.nih.gov/pubmed/19018252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2008.236
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