Enhanced Therapeutic Efficacy by Simultaneously Targeting Two Genetic Defects in Tumors

Targeting tumor-specific gene abnormalities has become an attractive approach in developing therapeutics to treat cancer. Overexpression of Bcl2 and mutations of p53 represent two of the most common molecular defects in tumors. In the nucleus, p53 induces cell cycle arrest, while it interacts with B...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Zhang, He, Wang, Haibo, Zhang, Jianjun, Qian, Guanxiang, Niu, Beibei, Fan, Xianqun, Lu, Jian, Hoffman, Andrew R., Hu, Ji-Fan, Ge, Shengfang
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2008
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834989/
https://ncbi.nlm.nih.gov/pubmed/19018252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2008.236
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker