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Putative tumor suppressor miR-145 inhibits colon cancer cell growth by targeting oncogene Friend leukemia virus integration 1

Tumor suppressor microRNA miR-145 is commonly down-regulated in colon carcinoma tissues, but its specific role in tumors remains unknown. In this study, we identify the Friend leukemia virus integration 1 gene (Fli-1) as a novel target of miR-145. Fli-1 is involved in t(11;22)(q24:q12) reciprocal ch...

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Autores principales: Zhang, Jianjun, Guo, Haiyan, Zhang, He, Wang, Haibo, Qian, Guanxiang, Fan, Xianqun, Hoffman, Andrew R., Hu, Ji-Fan, Ge, Shengfang
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995010/
https://ncbi.nlm.nih.gov/pubmed/20737575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.25522
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