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An acid-sensing ion channel from shark (Squalus acanthias) mediates transient and sustained responses to protons
Acid-sensing ion channels (ASICs) are proton-gated Na(+) channels. They are implicated in synaptic transmission, detection of painful acidosis, and possibly sour taste. The typical ASIC current is a transient, completely desensitizing current that can be blocked by the diuretic amiloride. ASICs are...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Blackwell Science Inc
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2834940/ https://ncbi.nlm.nih.gov/pubmed/20064854 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.182931 |
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