Small molecule activators of TRPML3

We conducted a high-throughput screen for small molecule activators of the TRPML3 ion channel which, when mutated, causes deafness and pigmentation defects. Cheminformatics analyses of the 53 identified and confirmed compounds revealed nine different chemical scaffolds and 20 singletons. We found th...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Main Authors: Grimm, Christian, Jörs, Simone, Saldanha, S. Adrian, Obukhov, Alexander G., Pan, Bifeng, Oshima, Kazuo, Cuajungco, Math P., Chase, Peter, Hodder, Peter, Heller, Stefan
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2010
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834294/
https://ncbi.nlm.nih.gov/pubmed/20189104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2009.12.016
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla