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Small molecule activators of TRPML3
We conducted a high-throughput screen for small molecule activators of the TRPML3 ion channel which, when mutated, causes deafness and pigmentation defects. Cheminformatics analyses of the 53 identified and confirmed compounds revealed nine different chemical scaffolds and 20 singletons. We found th...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2834294/ https://ncbi.nlm.nih.gov/pubmed/20189104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2009.12.016 |
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