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Life and Death of Sensory Hair Cells Expressing Constitutively Active TRPML3
The varitint-waddler mutation A419P renders TRPML3 constitutively active, resulting in cationic overload, particularly in sustained influx of Ca(2+). TRPML3 is expressed by inner ear sensory hair cells, and we were intrigued by the fact that hair cells are able to cope with expressing the TRPML3(A41...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2679483/ https://ncbi.nlm.nih.gov/pubmed/19299509 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M809045200 |
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