Differential Analgesic Effects of a Mu-Opioid Peptide, [Dmt(1)]DALDA, and Morphine

AIMS: H-Dmt-D-Arg-Phe-Lys-NH(2) ([Dmt(1)]DALDA), a highly selective μ-opioid peptide, is potently analgesic after systemic and intrathecal administration but is less potent given intracerebroventricularly. This study was performed to further characterize the analgesic effects of [Dmt(1)]DALDA. METHO...

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Detalhes bibliográficos
Main Authors: Shimoyama, Megumi, Szeto, Hazel H., Schiller, Peter W., Tagaito, Yugo, Tokairin, Hideyuki, Eun, Chong moon, Shimoyama, Naohito
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2008
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834256/
https://ncbi.nlm.nih.gov/pubmed/18987489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000167878
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