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The Bifunctional μ Opioid Agonist/Antioxidant [Dmt(1)]DALDA Is a Superior Analgesic in an Animal Model of Complex Regional Pain Syndrome-Type I

Reactive oxygen species (ROS) play an important role in the development of complex regional pain syndrome-Type I (CRPS-I), as also demonstrated with the chronic post ischemia pain (CPIP) animal model of CRPS-I. We show that morphine and the antioxidant N-acetylcysteine (NAC) act synergistically to r...

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Detalhes bibliográficos
Publicado no:ACS Chem Neurosci
Main Authors: Schiller, Peter W., Nguyen, Thi M.-D., Saray, Amy, Poon, Annie Wing Hoi, Laferrière, André, Coderre, Terence J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4651755/
https://ncbi.nlm.nih.gov/pubmed/26352668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.5b00228
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