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Differential Analgesic Effects of a Mu-Opioid Peptide, [Dmt(1)]DALDA, and Morphine

AIMS: H-Dmt-D-Arg-Phe-Lys-NH(2) ([Dmt(1)]DALDA), a highly selective μ-opioid peptide, is potently analgesic after systemic and intrathecal administration but is less potent given intracerebroventricularly. This study was performed to further characterize the analgesic effects of [Dmt(1)]DALDA. METHO...

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Main Authors: Shimoyama, Megumi, Szeto, Hazel H., Schiller, Peter W., Tagaito, Yugo, Tokairin, Hideyuki, Eun, Chong moon, Shimoyama, Naohito
格式: Artigo
語言:Inglês
出版: S. Karger AG 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834256/
https://ncbi.nlm.nih.gov/pubmed/18987489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000167878
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