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Fatal Transmissible Amyloid Encephalopathy: A New Type of Prion Disease Associated with Lack of Prion Protein Membrane Anchoring

Prion diseases are fatal neurodegenerative diseases of humans and animals characterized by gray matter spongiosis and accumulation of aggregated, misfolded, protease-resistant prion protein (PrPres). PrPres can be deposited in brain in an amyloid-form and/or non-amyloid form, and is derived from hos...

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Bibliografiske detaljer
Main Authors: Chesebro, Bruce, Race, Brent, Meade-White, Kimberly, LaCasse, Rachel, Race, Richard, Klingeborn, Mikael, Striebel, James, Dorward, David, McGovern, Gillian, Jeffrey, Martin
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832701/
https://ncbi.nlm.nih.gov/pubmed/20221436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000800
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