Fatal Transmissible Amyloid Encephalopathy: A New Type of Prion Disease Associated with Lack of Prion Protein Membrane Anchoring

Prion diseases are fatal neurodegenerative diseases of humans and animals characterized by gray matter spongiosis and accumulation of aggregated, misfolded, protease-resistant prion protein (PrPres). PrPres can be deposited in brain in an amyloid-form and/or non-amyloid form, and is derived from hos...

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Detalhes bibliográficos
Main Authors: Chesebro, Bruce, Race, Brent, Meade-White, Kimberly, LaCasse, Rachel, Race, Richard, Klingeborn, Mikael, Striebel, James, Dorward, David, McGovern, Gillian, Jeffrey, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832701/
https://ncbi.nlm.nih.gov/pubmed/20221436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000800
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