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Modulation of polyglutamine conformations and dimer formation by the N-terminus of Huntingtin
Polyglutamine expansions within different proteins are associated with nine different neurodegenerative diseases. There is growing interest in understanding the roles of flanking sequences from disease-relevant proteins on the intrinsic conformational and aggregation properties of polyglutamine. We...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2832287/ https://ncbi.nlm.nih.gov/pubmed/20026071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.12.017 |
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