Llwytho...

Altered gene expression in the Werner and Bloom syndromes is associated with sequences having G-quadruplex forming potential

The human Werner and Bloom syndromes (WS and BS) are caused by deficiencies in the WRN and BLM RecQ helicases, respectively. WRN, BLM and their Saccharomyces cerevisiae homologue Sgs1, are particularly active in vitro in unwinding G-quadruplex DNA (G4-DNA), a family of non-canonical nucleic acid str...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Johnson, Jay E., Cao, Kajia, Ryvkin, Paul, Wang, Li-San, Johnson, F. Brad
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2831322/
https://ncbi.nlm.nih.gov/pubmed/19966276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1103
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