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Telomeric repeat-containing RNA/G-quadruplex-forming sequences cause genome-wide alteration of gene expression in human cancer cells in vivo

Telomere erosion causes cell mortality, suggesting that longer telomeres enable more cell divisions. In telomerase-positive human cancer cells, however, telomeres are often kept shorter than those of surrounding normal tissues. Recently, we showed that cancer cell telomere elongation represses innat...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Hirashima, Kyotaro, Seimiya, Hiroyuki
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4344506/
https://ncbi.nlm.nih.gov/pubmed/25653161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv063
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