Intragenic G-quadruplex structure formed in the human CD133 and its biological and translational relevance

Cancer stem cells (CSCs) have been identified in several solid malignancies and are now emerging as a plausible target for drug discovery. Beside the questionable existence of CSCs specific markers, the expression of CD133 was reported to be responsible for conferring CSC aggressiveness. Here, we id...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:Nucleic Acids Res
المؤلفون الرئيسيون: Zizza, Pasquale, Cingolani, Chiara, Artuso, Simona, Salvati, Erica, Rizzo, Angela, D'Angelo, Carmen, Porru, Manuela, Pagano, Bruno, Amato, Jussara, Randazzo, Antonio, Novellino, Ettore, Stoppacciaro, Antonella, Gilson, Eric, Stassi, Giorgio, Leonetti, Carlo, Biroccio, Annamaria
التنسيق: Artigo
اللغة:Inglês
منشور في: Oxford University Press 2016
الموضوعات:
Gene regulation, Chromatin and Epigenetics
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770210/
https://ncbi.nlm.nih.gov/pubmed/26511095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1122
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