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Precise targeted integration by a chimaeric transposase zinc-finger fusion protein
Transposons of the Tc1/mariner family have been used to integrate foreign DNA stably into the genome of a large variety of different cell types and organisms. Integration is at TA dinucleotides located essentially at random throughout the genome, potentially leading to insertional mutagenesis, inapp...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2831304/ https://ncbi.nlm.nih.gov/pubmed/19965773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1068 |
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