Sequence-specific DNA binding activity of the cross-brace zinc finger motif of the piggyBac transposase

The piggyBac transposase (PB) is distinguished by its activity and utility in genome engineering, especially in humans where it has highly promising therapeutic potential. Little is known, however, about the structure–function relationships of the different domains of PB. Here, we demonstrate in vit...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Morellet, Nelly, Li, Xianghong, Wieninger, Silke A, Taylor, Jennifer L, Bischerour, Julien, Moriau, Séverine, Lescop, Ewen, Bardiaux, Benjamin, Mathy, Nathalie, Assrir, Nadine, Bétermier, Mireille, Nilges, Michael, Hickman, Alison B, Dyda, Fred, Craig, Nancy L, Guittet, Eric
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
Matèries:
Structural Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5861402/
https://ncbi.nlm.nih.gov/pubmed/29385532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky044
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