Sequence-specific DNA binding activity of the cross-brace zinc finger motif of the piggyBac transposase

The piggyBac transposase (PB) is distinguished by its activity and utility in genome engineering, especially in humans where it has highly promising therapeutic potential. Little is known, however, about the structure–function relationships of the different domains of PB. Here, we demonstrate in vit...

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Enregistré dans:
Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Morellet, Nelly, Li, Xianghong, Wieninger, Silke A, Taylor, Jennifer L, Bischerour, Julien, Moriau, Séverine, Lescop, Ewen, Bardiaux, Benjamin, Mathy, Nathalie, Assrir, Nadine, Bétermier, Mireille, Nilges, Michael, Hickman, Alison B, Dyda, Fred, Craig, Nancy L, Guittet, Eric
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2018
Sujets:
Structural Biology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5861402/
https://ncbi.nlm.nih.gov/pubmed/29385532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky044
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