Sequence-specific DNA binding activity of the cross-brace zinc finger motif of the piggyBac transposase

The piggyBac transposase (PB) is distinguished by its activity and utility in genome engineering, especially in humans where it has highly promising therapeutic potential. Little is known, however, about the structure–function relationships of the different domains of PB. Here, we demonstrate in vit...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Morellet, Nelly, Li, Xianghong, Wieninger, Silke A, Taylor, Jennifer L, Bischerour, Julien, Moriau, Séverine, Lescop, Ewen, Bardiaux, Benjamin, Mathy, Nathalie, Assrir, Nadine, Bétermier, Mireille, Nilges, Michael, Hickman, Alison B, Dyda, Fred, Craig, Nancy L, Guittet, Eric
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2018
Assuntos:
Structural Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5861402/
https://ncbi.nlm.nih.gov/pubmed/29385532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky044
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