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Genesis of cerebellar interneurons and the prevention of neural DNA damage require XRCC1

Defective responses to DNA single strand breaks underpin various neurodegenerative diseases. However, the exact role of this repair pathway during development and maintenance of the nervous system is unclear. Using murine neural-specific inactivation of Xrcc1, a factor critical for the repair of DNA...

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Hlavní autoři: Lee, Youngsoo, Katyal, Sachin, Li, Yang, El-Khamisy, Sherif F., Russell, Helen R., Caldecott, Keith W., McKinnon, Peter J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2831284/
https://ncbi.nlm.nih.gov/pubmed/19633665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2375
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