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Genesis of cerebellar interneurons and the prevention of neural DNA damage require XRCC1

Defective responses to DNA single strand breaks underpin various neurodegenerative diseases. However, the exact role of this repair pathway during development and maintenance of the nervous system is unclear. Using murine neural-specific inactivation of Xrcc1, a factor critical for the repair of DNA...

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書誌詳細
主要な著者: Lee, Youngsoo, Katyal, Sachin, Li, Yang, El-Khamisy, Sherif F., Russell, Helen R., Caldecott, Keith W., McKinnon, Peter J.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2831284/
https://ncbi.nlm.nih.gov/pubmed/19633665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2375
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