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Lestaurtinib Enhances the Anti-tumor Efficacy of Chemotherapy in Murine Xenograft Models of Neuroblastoma

PURPOSE: Neuroblastoma, a common pediatric tumor of the sympathetic nervous system, is characterized by clinical heterogeneity, and the Trk family neurotrophin receptors play an important role in this behavior. Expression of TrkA is associated with favorable clinical features and outcome, whereas Tr...

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Main Authors: Iyer, Radhika, Evans, Audrey E., Qi, Xiaoxue, Ho, Ruth, Minturn, Jane E., Zhao, Huaqing, Balamuth, Naomi, Maris, John M., Brodeur, Garrett M.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2831131/
https://ncbi.nlm.nih.gov/pubmed/20179224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-1531
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