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Preclinical evaluation of lestaurtinib (CEP-701) in combination with retinoids for neuroblastoma

PURPOSE: Lestaurtinib (CEP-701), a multi-kinase inhibitor with potent activity against the Trk family of receptor tyrosine kinases, has undergone early phase clinical evaluation in children with relapsed neuroblastoma. We studied the interaction of CEP-701 with isotretinoin (13cRA) and fenretinide (...

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書誌詳細
主要な著者: Norris, Robin E., Minturn, Jane E., Brodeur, Garrett M., Maris, John M., Adamson, Peter C.
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135359/
https://ncbi.nlm.nih.gov/pubmed/21484309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-011-1623-y
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