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Puromycin-Sensitive Aminopeptidase: An Antiviral Prodrug Activating Enzyme
Cidofovir (HPMPC) is a broad-spectrum antiviral agent, currently used to treat AIDS-related human cytomegalovirus retinitis. Cidofovir has recognized therapeutic potential for orthopox virus infections, although its use is hampered by its inherent low oral bioavailability. Val-Ser-cyclic HPMPC (Val-...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2830364/ https://ncbi.nlm.nih.gov/pubmed/19969024 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2009.12.003 |
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