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Prodrug approaches to improving the oral absorption of antiviral nucleotide analogues
Nucleotide analogues have been well accepted as therapeutic agents active against a number of viruses. However, their use as antiviral agents is limited by the need for phosphorylation by endogenous enzymes, and if the analogue is orally administered, by low bioavailability due to the presence of an...
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| Veröffentlicht in: | Expert Opin Drug Deliv |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5117106/ https://ncbi.nlm.nih.gov/pubmed/19382883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/17425240902824808 |
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