PAI-1 Regulates the Invasive Phenotype in Human Cutaneous Squamous Cell Carcinoma

The emergence of highly aggressive subtypes of human cutaneous squamous cell carcinoma (SCC) often reflects increased autocrine/paracrine TGF-β synthesis and epidermal growth factor receptor (EGFR) amplification. Cooperative TGF-β/EGFR signaling promotes cell migration and induces expression of both...

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Detalhes bibliográficos
Main Authors: Freytag, Jennifer, Wilkins-Port, Cynthia E., Higgins, Craig E., Carlson, J. Andrew, Noel, Agnes, Foidart, Jean-Michel, Higgins, Stephen P., Samarakoon, Rohan, Higgins, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2009
Assuntos:
Review Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829771/
https://ncbi.nlm.nih.gov/pubmed/20204159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2009/963209
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