TGF-β1 + EGF-Initiated Invasive Potential in Transformed Human Keratinocytes Is Coupled to a Plasmin/MMP-10/MMP-1–Dependent Collagen Remodeling Axis: Role for PAI-1

Por Wilkins-Port, Cynthia E., Ye, Qunhui, Mazurkiewicz, Joseph E., Higgins, Paul J.
Publicado em 2009

Complex Regulation of the Pericellular Proteolytic Microenvironment during Tumor Progression and Wound Repair: Functional Interactions between the Serine Protease and Matrix Metall...

Por Wilkins-Port, Cynthia E., Higgins, Stephen P., Higgins, Craig E., Kobori-Hotchkiss, Issey, Higgins, Paul J.
Publicado em 2012

TGF-β1-Induced Expression of the Anti-Apoptotic PAI-1 Protein Requires EGFR Signaling

Por Higgins, Stephen P., Samarakoon, Rohan, Higgins, Craig E., Freytag, Jennifer, Wilkins-Port, Cynthia E., Higgins, Paul J.
Publicado em 2009

PAI-1 Mediates the TGF-β1+EGF-Induced “Scatter” Response in Transformed Human Keratinocytes

Por Freytag, Jennifer, Wilkins-Port, Cynthia E., Higgins, Craig E., Higgins, Stephen P., Samarakoon, Rohan, Higgins, Paul J.
Publicado em 2010

PAI-1 is a Critical Upstream Regulator of the TGF-β1/EGF-Induced Invasive Phenotype in Mutant p53 Human Cutaneous Squamous Cell Carcinoma

Por Wilkins-Port, Cynthia E., Higgins, Craig E., Freytag, Jennifer, Higgins, Stephen P., Carlson, J. Andrew, Higgins, Paul J.
Publicado em 2007

SERPINE1 (PAI-1) is deposited into keratinocyte migration “trails” and required for optimal monolayer wound repair

Por Providence, Kirwin M., Higgins, Stephen P., Mullen, Andrew, Battista, Ashley, Samarakoon, Rohan, Higgins, Craig E., Wilkins-Port, Cynthia E., Higgins, Paul J.
Publicado em 2008

SERPINE1 (PAI-1) Is a Prominent Member of the Early G(0)→G(1) Transition “Wound Repair” Transcriptome in p53 Mutant Human Keratinocytes

Por Qi, Li, Higgins, Stephen P., Lu, Qi, Samarakoon, Rohan, Wilkins-Port, Cynthia E., Ye, Qunhui, Higgins, Craig E., Staiano-Coico, Lisa, Higgins, Paul J.
Publicado em 2007

PAI-1 Regulates the Invasive Phenotype in Human Cutaneous Squamous Cell Carcinoma

Por Freytag, Jennifer, Wilkins-Port, Cynthia E., Higgins, Craig E., Carlson, J. Andrew, Noel, Agnes, Foidart, Jean-Michel, Higgins, Stephen P., Samarakoon, Rohan, Higgins, Paul J.
Publicado em 2009

PAI-1: An Integrator of Cell Signaling and Migration

Por Czekay, Ralf-Peter, Wilkins-Port, Cynthia E., Higgins, Stephen P., Freytag, Jennifer, Overstreet, Jessica M., Klein, R. Matthew, Higgins, Craig E., Samarakoon, Rohan, Higgins, Paul J.
Publicado em 2011