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PAI-1 Mediates the TGF-β1+EGF-Induced “Scatter” Response in Transformed Human Keratinocytes

Cooperative interactions between growth factor signaling pathways are important elements in carcinoma progression. A model system combining transforming growth factor-β1 (TGF-β1) and EGF was developed to investigate mechanisms underlying induced epithelial-to-mesenchymal transition (EMT) in ras-tran...

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Detalhes bibliográficos
Main Authors: Freytag, Jennifer, Wilkins-Port, Cynthia E., Higgins, Craig E., Higgins, Stephen P., Samarakoon, Rohan, Higgins, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774605/
https://ncbi.nlm.nih.gov/pubmed/20428185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2010.106
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