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TGF-β1-Induced Expression of the Anti-Apoptotic PAI-1 Protein Requires EGFR Signaling

TGF-β1 and its target gene encoding plasminogen activator inhibitor-1 (PAI-1) are major regulators of capillary outgrowth, vessel maturation and angiogenic network stability. The increasing realization of the complexity of PAI-1 action in the vascular system requires analysis of specific signaling e...

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Detalhes bibliográficos
Main Authors: Higgins, Stephen P., Samarakoon, Rohan, Higgins, Craig E., Freytag, Jennifer, Wilkins-Port, Cynthia E., Higgins, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953848/
https://ncbi.nlm.nih.gov/pubmed/20953304
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