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The Importance of Being Tyrosine: Lessons in Molecular Recognition from Minimalist Synthetic Binding Proteins

Combinatorial libraries built with severely restricted chemical diversity have yielded highly functional synthetic binding proteins. Structural analyses of these minimalist binding sites have revealed the dominant role of large tyrosine residues for mediating molecular contacts and of small serine/g...

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Hlavní autoři: Koide, Shohei, Sidhu, Sachdev S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829252/
https://ncbi.nlm.nih.gov/pubmed/19298050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb800314v
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