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The Importance of Being Tyrosine: Lessons in Molecular Recognition from Minimalist Synthetic Binding Proteins

Combinatorial libraries built with severely restricted chemical diversity have yielded highly functional synthetic binding proteins. Structural analyses of these minimalist binding sites have revealed the dominant role of large tyrosine residues for mediating molecular contacts and of small serine/g...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Koide, Shohei, Sidhu, Sachdev S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829252/
https://ncbi.nlm.nih.gov/pubmed/19298050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb800314v
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