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Essential Role of the p110β Subunit of Phosphoinositide 3-OH Kinase in Male Fertility

Phosphoinositide 3-kinases (PI3K) are key molecular players in male fertility. However, the specific roles of different p110 PI3K catalytic subunits within the spermatogenic lineage have not been characterized so far. Herein, we report that male mice expressing a catalytically inactive p110β develop...

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Autors principals: Ciraolo, Elisa, Morello, Fulvio, Hobbs, Robin M., Wolf, Frieder, Marone, Romina, Iezzi, Manuela, Lu, Xiaoyun, Mengozzi, Giulio, Altruda, Fiorella, Sorba, Giovanni, Guan, Kaomei, Pandolfi, Pier Paolo, Wymann, Matthias P., Hirsch, Emilio
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828958/
https://ncbi.nlm.nih.gov/pubmed/20053680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-08-0744
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