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Essential Role of the p110β Subunit of Phosphoinositide 3-OH Kinase in Male Fertility

Phosphoinositide 3-kinases (PI3K) are key molecular players in male fertility. However, the specific roles of different p110 PI3K catalytic subunits within the spermatogenic lineage have not been characterized so far. Herein, we report that male mice expressing a catalytically inactive p110β develop...

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Détails bibliographiques
Auteurs principaux: Ciraolo, Elisa, Morello, Fulvio, Hobbs, Robin M., Wolf, Frieder, Marone, Romina, Iezzi, Manuela, Lu, Xiaoyun, Mengozzi, Giulio, Altruda, Fiorella, Sorba, Giovanni, Guan, Kaomei, Pandolfi, Pier Paolo, Wymann, Matthias P., Hirsch, Emilio
Format: Artigo
Langue:Inglês
Publié: The American Society for Cell Biology 2010
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828958/
https://ncbi.nlm.nih.gov/pubmed/20053680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-08-0744
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