Phosphoinositide 3-Kinase p110β activity: Key Role in Metabolism and Mammary Gland Cancer but not Development

The phosphoinositide 3-kinase (PI3K) pathway crucially controls metabolism and cell growth. Although different PI3K catalytic subunits are known to play distinct roles, the specific in vivo function of p110β (the product of the PIK3CB gene) is not clear. Here, we show that mouse mutants expressing a...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Ciraolo, Elisa, Iezzi, Manuela, Marone, Romina, Marengo, Stefano, Curcio, Claudia, Costa, Carlotta, Azzolino, Ornella, Gonella, Cristiano, Rubinetto, Cristina, Wu, Haiyan, Dastrù, Walter, Martin, Erica L., Silengo, Lorenzo, Altruda, Fiorella, Turco, Emilia, Lanzetti, Letizia, Musiani, Piero, Rückle, Thomas, Rommel, Christian, Backer, Jonathan M., Forni, Guido, Wymann, Matthias P., Hirsch, Emilio
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2694958/
https://ncbi.nlm.nih.gov/pubmed/18780892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.1161577
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge