Phosphoinositide 3-Kinase p110β activity: Key Role in Metabolism and Mammary Gland Cancer but not Development

The phosphoinositide 3-kinase (PI3K) pathway crucially controls metabolism and cell growth. Although different PI3K catalytic subunits are known to play distinct roles, the specific in vivo function of p110β (the product of the PIK3CB gene) is not clear. Here, we show that mouse mutants expressing a...

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Main Authors: Ciraolo, Elisa, Iezzi, Manuela, Marone, Romina, Marengo, Stefano, Curcio, Claudia, Costa, Carlotta, Azzolino, Ornella, Gonella, Cristiano, Rubinetto, Cristina, Wu, Haiyan, Dastrù, Walter, Martin, Erica L., Silengo, Lorenzo, Altruda, Fiorella, Turco, Emilia, Lanzetti, Letizia, Musiani, Piero, Rückle, Thomas, Rommel, Christian, Backer, Jonathan M., Forni, Guido, Wymann, Matthias P., Hirsch, Emilio
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2694958/
https://ncbi.nlm.nih.gov/pubmed/18780892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.1161577
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