Defective Dendrite Elongation but Normal Fertility in Mice Lacking the Rho-Like GTPase Activator Dbl

Dbl is the prototype of a large family of GDP-GTP exchange factors for small GTPases of the Rho family. In vitro, Dbl is known to activate Rho and Cdc42 and to induce a transformed phenotype. Dbl is specifically expressed in brain and gonads, but its in vivo functions are largely unknown. To assess...

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Bibliographic Details
Main Authors: Hirsch, Emilio, Pozzato, Michela, Vercelli, Alessandro, Barberis, Laura, Azzolino, Ornella, Russo, Chiara, Vanni, Cristina, Silengo, Lorenzo, Eva, Alessandra, Altruda, Fiorella
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC133768/
https://ncbi.nlm.nih.gov/pubmed/11940671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.9.3140-3148.2002
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