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Ablation of Phosphoinositide 3-Kinase-γ Reduces the Severity of Acute Pancreatitis

In pancreatic acini, the G-protein-activated phosphoinositide 3-kinase-γ (PI3Kγ) regulates several key pathological responses to cholecystokinin hyperstimulation in vitro. Thus, using mice lacking PI3Kγ, we studied the function of this enzyme in vivo in two different models of acute pancreatitis. Th...

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書誌詳細
主要な著者: Lupia, Enrico, Goffi, Alberto, De Giuli, Paolo, Azzolino, Ornella, Bosco, Ornella, Patrucco, Enrico, Vivaldo, Maria Cristina, Ricca, Marco, Wymann, Matthias P., Hirsch, Emilio, Montrucchio, Giuseppe, Emanuelli, Giorgio
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Investigative Pathology 2004
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618701/
https://ncbi.nlm.nih.gov/pubmed/15579443
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