Ras is an indispensable coregulator of the class I(B) phosphoinositide 3-kinase p87/p110γ

Class I(B) phosphoinositide 3-kinase γ (PI3Kγ) elicits various immunologic and cardiovascular responses; however, the molecular basis for this signal heterogeneity is unclear. PI3Kγ consists of a catalytic p110γ and a regulatory p87(PIKAP) (p87, also p84) or p101 subunit. Hitherto p87 and p101 are g...

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Bibliographische Detailangaben
Hauptverfasser: Kurig, Barbara, Shymanets, Aliaksei, Bohnacker, Thomas, Prajwal, Brock, Carsten, Ahmadian, Mohammad Reza, Schaefer, Michael, Gohla, Antje, Harteneck, Christian, Wymann, Matthias P., Jeanclos, Elisabeth, Nürnberg, Bernd
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2009
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787109/
https://ncbi.nlm.nih.gov/pubmed/19906996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0905506106
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